The Annals of pharmacotherapy
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To compare the different sterility standards and the cost issues involved when choosing an opioid product for intraspinal administration. ⋯ The preservative-free commercially available products that are indicated for intrathecal/epidural use are the best alternative due to proper outside testing and stringent quality assurance. The generic morphine preservative-free product may also be considered if proper steps are taken to ensure that the final product is diluted properly.