The Annals of pharmacotherapy
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To describe a case of levetiracetam-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. ⋯ Although levetiracetam is usually well tolerated, clinicians should be aware of the potential for it to cause DRESS syndrome.
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Case Reports
Rectal bleeding and hemostatic disorders induced by dabigatran etexilate in 2 elderly patients.
To report rectal bleeding associated with hemostatic disorders in 2 elderly patients treated with dabigatran etexilate. ⋯ It is critical to identify and subsequently manage dabigatran etexilate toxicity because there is no specific antidote to reverse the drug's anticoagulant effects.
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Postoperative atrial fibrillation (POAF) is a frequent complication following cardiothoracic surgery and is associated with an increase in morbidity, mortality, and cost. One small prospective study of patients undergoing isolated coronary artery bypass graft surgery has demonstrated a decrease in the risk of POAF with the use of sodium nitroprusside. ⋯ There was no significant association between the use of sodium nitroprusside during cardiothoracic surgery and POAF.
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To evaluate the efficacy and safety of the polypill for prevention of cardiovascular disease (CVD) and stroke and to present literature related to the polypill components (statin, aspirin, antihypertensive) for primary prevention of CVD and stroke. ⋯ Polypill study results have been more modest than originally theorized. However, results show promise in patients at higher risk for CVD and stroke.