Journal of vascular and interventional radiology : JVIR
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J Vasc Interv Radiol · Jul 2006
Diffusion-weighted MR imaging for determination of hepatocellular carcinoma response to yttrium-90 radioembolization.
Early detection of the response of hepatocellular carcinoma (HCC) to yttrium-90 radioembolization therapy may be important to permit repeat radioembolization or alternative treatment options. Water-mobility measurements with use of diffusion-weighted (DW) magnetic resonance (MR) imaging are useful for noninvasive interrogation of microstructural tissue properties. ⋯ In each of six patients with HCC included in the study, tumor water diffusion increased significantly after therapy. DW MR imaging is a promising technique for noninvasive assessment of tumor response to (90)Y radioembolization.