Lupus
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Meta Analysis
Association between the CD226 rs763361 polymorphism and susceptibility to autoimmune diseases: a meta-analysis.
The aim of this study was to explore whether the CD226 rs763361 polymorphism confers susceptibility to autoimmune diseases. ⋯ This meta-analysis demonstrates the CD226 rs763361 polymorphism confers susceptibility to autoimmune disease in Europeans, South Americans and Asians, and in particular, shows that the CD226 rs763361 polymorphism is associated with SLE, SSc and T1D. These results support the existence of an association between the CD226 gene and a subgroup of autoimmune diseases.