Journal of diabetes and its complications
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J. Diabetes Complicat. · Jan 2006
Randomized Controlled TrialTreatment of intractable painful diabetic neuropathy with intravenous lignocaine.
Lignocaine is a cardiac antiarrhythmic agent occasionally used to treat neuropathic pain. This study was designed to examine the effectiveness of intravenous lignocaine in patients with intractable painful diabetic neuropathy. ⋯ This study shows that intravenous lignocaine ameliorates pain in some diabetic participants with intractable neuropathic pain who have failed to respond to or are intolerant of available conventional therapy.
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J. Diabetes Complicat. · Jan 2006
Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns.
To determine the patient burden of painful diabetic peripheral neuropathy (DPN) with respect to pain intensity and impact on patient functioning and to characterize relevant DPN treatment patterns. ⋯ Painful DPN is associated with substantial patient burden resulting from interference with daily functioning, especially in patients with suboptimal pain management.
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J. Diabetes Complicat. · Jan 2006
Trends in heart disease death rates in diabetic and nondiabetic Pima Indians.
Secular trends over 34 years (1965-1998) in overall and cause-specific mortality were examined in 4,623 Pima Indians >or=35 years old. ⋯ The rate of death from IHD remained stable in nondiabetic Pima Indians but increased among those with diabetes. This finding suggests that, in the absence of diabetes, the underlying susceptibility to IHD in this population has not changed.