Journal of diabetes and its complications
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J. Diabetes Complicat. · Jan 2009
Randomized Controlled Trial Multicenter StudyFrequency-modulated electromagnetic neural stimulation enhances cutaneous microvascular flow in patients with diabetic neuropathy.
The aim of this study was to investigate the effects of frequency modulated electromagnetic neural stimulation (FREMS), a recently developed safe and effective treatment of painful diabetic neuropathy, on cutaneous microvascular function. ⋯ These results indicate that 10 treatments with FREMS may induce an enhancement of microvascular blood flow measurable at 4 months of follow-up. The findings of this study will need to be confirmed in a larger, adequately powered study (ClinicalTrial.gov Id: NCT00337324).
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J. Diabetes Complicat. · Jan 2009
Clinical TrialEffect and safety of spinal cord stimulation for treatment of chronic pain caused by diabetic neuropathy.
Spinal cord stimulation (SCS) has been shown effective as a therapy for different chronic painful conditions, but the effectiveness of this treatment for pain as a result of peripheral diabetic neuropathy is not well established. The primary objectives of this study were to evaluate the effect and safety of SCS for treatment of pain and the effects on microcirculatory blood flow in the affected areas in patients with refractory peripheral diabetic neuropathy. ⋯ Spinal cord stimulation offers an effective and safe therapy for chronic diabetic neuropathic pain.