Paediatric anaesthesia
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Paediatric anaesthesia · Jun 2004
Comparative StudyCurrent patterns of propofol use in PICU in the United Kingdom and North America.
Our aim was to investigate the current patterns of propofol use in pediatric intensive care units (PICUs) in the UK and North America. ⋯ Despite clear guidance from the UK Committee on Safety of Medicines, propofol was still used for ongoing sedation in 47% of UK PICUs responding to our questionnaire. Reasons for this include the utility of the agent and its licensing for use in maintaining anesthesia in children over 3 years, but not for sedation in PICU in similar doses, for similar periods, in the same group of children.
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Propofol is a well-known drug for adults for total intravenous anaesthesia. Since 1999, the use of propofol has been approved for children less than 3 years of age. However, a suitable dosage scheme for these age groups was not available. The purpose of this study was to describe our clinical experience with the use of a new dosage scheme for propofol in patients under 3 years of age, based on experimental data and known pharmacological principles in children. ⋯ This dosage scheme provides safe and smooth anaesthesia in children less than 3 years of age and is therefore a useful tool for a TIVA technique in small children.
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Paediatric anaesthesia · Jun 2004
Randomized Controlled Trial Comparative Study Clinical TrialComparison of ropivacaine with bupivacaine and lidocaine for ilioinguinal block after ambulatory inguinal hernia repair in children.
We have compared ropivacaine with bupivacaine and lidocaine for ilioinguinal block in thirty children undergoing ambulatory inguinal hernia repair. ⋯ We have confirmed that bupivacaine and ropivacaine are more effective than lidocaine in the prevention of postoperative pain after children's inguinal hernia repair. We suggest that ropivacaine 0.2% is an alternative to bupivacaine 0.25% for ilioinguinal block in ambulatory paediatric surgery.