Paediatric anaesthesia
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Paediatric anaesthesia · Feb 2014
Effect of general anesthesia on pulmonary function and clinical status on children with cystic fibrosis.
Children with cystic fibrosis (CF) receive general anesthesia (GA) for a variety of different procedures. Historical studies assessing risk of GA report a high risk of morbidity. There is a paucity of data evaluating the risk of currently available anesthetic agents. The aim of this study was to assess the effect of GA on clinical status and lung function on children with CF. ⋯ The results suggest that children with mild to moderate CF lung disease do not experience significant deterioration in central or peripheral airway function following GA. The low rate of complications suggests an improved level of safety for children with CF with modern anesthesia compared with historical published data.
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Paediatric anaesthesia · Feb 2014
Randomized Controlled TrialAprotinin and transfusion requirements in pediatric craniofacial surgery.
To evaluate transfusion requirements in children receiving aprotinin during craniofacial surgery. ⋯ Aprotinin was associated with decreased packed red blood cell transfusion requirements in children undergoing craniofacial surgery, with no renal toxicity or death. Aprotinin is no longer available for clinical use in the USA because of adverse effects in adults; re-evaluation of aprotinin is warranted for children scheduled to undergo surgery involving potentially high blood loss.
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Paediatric anaesthesia · Feb 2014
Development and validation of the Pediatric Anesthesia Behavior score - an objective measure of behavior during induction of anesthesia.
Measuring perioperative behavior changes requires validated objective rating scales. We developed a simple score for children's behavior during induction of anesthesia (Pediatric Anesthesia Behavior score) and assessed its reliability, concurrent validity, and predictive validity. ⋯ The PAB score is simple to use and may predict which children are at increased risk of developing postoperative behavioral disturbance. This study provides evidence for its reliability and validity.
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Paediatric anaesthesia · Feb 2014
Historical ArticleThe development of pediatric fluid resuscitation: an interview with Dr. Frederic A. 'Fritz' Berry.
Dr. Frederic A. 'Fritz' Berry (1935), Professor Emeritus of Anesthesiology and Pediatrics at the University of Virginia, has played a pioneering role in the development of pediatric anesthesiology through training generations of anesthesiologists. ⋯ He imparted these and other insights to his colleagues although textbooks, book chapters, original journal publications, and decades of Refresher Course Lectures at the American Society of Anesthesiologists' annual meetings. A model educator, clinician, and researcher, he shaped the careers of hundreds of physicians-in-training while advancing the field of pediatric anesthesiology.