Paediatric anaesthesia
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Paediatric anaesthesia · Mar 2014
Randomized Controlled Trial Comparative StudyThe sedative effects and the attenuation of cardiovascular and arousal responses during anesthesia induction and intubation in pediatric patients: a randomized comparison between two different doses of preoperative intranasal dexmedetomidine.
Premedication with intranasal dexmedetomidine (DEX) has shown to be an effective sedative in pediatric patients. This prospective, randomized, and controlled investigation was designed to evaluate whether the difference in intranasal DEX dosing would produce different beneficial effects on the attenuation of cardiovascular and arousal responses during anesthesia induction and intubation. ⋯ Intranasal DEX 2 μg·kg(-1) administered 30 min before anesthesia induction provides considerable effect to attenuate the increase in MAP caused by intubation response. Changes in HR and BIS also demonstrate that this kind of premedication provides effective attenuation of intubation response. And preoperative intranasal DEX 2 μg·kg(-1) produces optimal-sedation, more favorable anesthesia induction course in pediatric patients. Premedication of intranasal DEX is a considerable way to blunt cardiovascular and arousal responses to endotracheal intubation.
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Paediatric anaesthesia · Mar 2014
Randomized Controlled TrialImplicit memory formation using the word stem completion task during anesthesia in children.
To determine whether there is evidence of implicit memory formation during pediatric anesthesia using the word stem completion task. ⋯ This study found no strong evidence that children form implicit memories for auditory words during anesthesia. Given the difference between lists, future research is warranted using carefully chosen word stems.
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Paediatric anaesthesia · Mar 2014
Randomized Controlled TrialEffects of promethazine or dexamethasone pretreatment on mivacurium-induced histamine release in children.
To determine the effects of pretreatment with either promethazine or dexamethasone on mivacurium-induced histamine release in children. ⋯ Pretreatment with promethazine significantly decreased mivacurium-induced histamine release in children and provided stable hemodynamics during administration of anesthesia.