Paediatric anaesthesia
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Paediatric anaesthesia · Feb 2019
What are the validity and reliability of the modified Yale Preoperative Anxiety Scale-Short Form in children less than 2 years old?
Accurate measurement of preoperative anxiety is important for pediatric surgical patients' care as well as for monitoring anxiety-reducing interventions. The modified Yale Preoperative Anxiety Scale-short form is well validated for this purpose in children aged 2 years and above, but not in younger children. ⋯ These findings support the validity and reliability of the Dutch version of the modified Yale Preoperative Anxiety Scale-short form in children less than 2-years-old.
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Paediatric anaesthesia · Feb 2019
Review Meta AnalysisA Systematic Review and Narrative Synthesis on the histological and neurobehavioral long term effects of dexmedetomidine.
Recent experimental studies suggest that currently used anesthetics have neurotoxic effects on young animals. Clinical studies are increasingly publishing about the effects of anesthesia on the long-term outcome, providing contradictory results. The selective alpha-2 adrenergic receptor agonist dexmedetomidine has been suggested as an alternative nontoxic sedative agent. ⋯ In animals, dexmedetomidine was found not to induce histologic injury and to show a beneficial effect when administered with another anesthetic. No clinical results on the long-term effects in children have been identified yet.
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Paediatric anaesthesia · Feb 2019
Quality control and stability of ketamine, remifentanil, and sufentanil syringes in a pediatric operating theater.
Transforming a drug from its commercial form into a ready-to-use drug is common practice, especially in pediatrics. However, the risk of compounding error is real and data on drug stability in practice are not always available. ⋯ The study shows that stock solution syringes prepared in advance are chemically stable throughout the day, unlike certain serial dilution syringes, indicating that the latter should be prepared just before administration to ensure chemical stability. Our results show that the error rate for serial dilution syringes is twice that of stock solution. Different safety measures are under discussion and have to be further studied.
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Paediatric anaesthesia · Feb 2019
Observational StudyPostoperative behavioral changes in Chinese children undergoing hypospadias repair surgery: A prospective cohort study.
The perioperative period can be psychologically challenging, and children may exhibit behavioral changes following surgical anesthesia. It is unknown whether children in China have additional risk factors associated with negative behavioral changes. ⋯ For children undergoing hypospadias repair surgery in our institution, approximately three in five showed postoperative behavioral changes. In addition to a younger age and a higher maternal education, an emotional temperament is associated with a high incidence of negative postoperative behavioral changes.