Paediatric anaesthesia
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Paediatric anaesthesia · Jun 2020
Letter Case ReportsEmergency surgery during the COVID-19 pandemic.
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Paediatric anaesthesia · May 2020
Randomized Controlled TrialUltrasonographic evaluation of gastric emptying after ingesting carbohydrate-rich drink in young children: A randomized crossover study.
A recent consensus statement in Europe has suggested that the fasting time for clear liquid in children can be shortened to 1 hour before a surgery. However, the study to show that 1-hour fasting time for clear fluids is safe in young children is still lacking. This study aimed to investigate the gastric emptying time for carbohydrate-rich drink and regular 5% glucose solution in children aged 3-7 years. ⋯ Gastric emptying of carbohydrate-rich drink is slower than that of 5% glucose solution but the residual gastric fluid volume is low one hour after ingestion of 5 mL kg-1 of either fluid.
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Paediatric anaesthesia · May 2020
Randomized Controlled TrialPharmacokinetics of an intravenous bolus dose of clonidine in children undergoing surgery.
Clonidine is used off-label in children but only limited pediatric pharmacokinetic data are available for intravenously administered clonidine. ⋯ Pharmacokinetic parameter estimates were similar for children undergoing general surgery and cardiac surgery given a single dose of intravenous clonidine. These results indicated that no dose reduction is needed in children aged 1 to <2 years compared with those 2-5 years, which was supported by pharmacodynamic observations.