Paediatric anaesthesia
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Paediatric anaesthesia · Mar 2009
Sedation medication received and adverse events related to sedation for brain MRI in children with and without developmental disabilities.
There are few studies on sedation medication requirements and sedation related adverse events in developmentally disabled children. ⋯ Children with developmental disabilities have similar requirements for sedation medications but are three times more likely to experience hypoxia when compared with normal children.
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The alpha2 agonist clonidine has become a popular drug for premedication in children. Effects and pharmacokinetics after oral, rectal, and intravenous administration are well known. The aim of this study was to investigate the absorption pharmacokinetics of clonidine nasal drops in children. ⋯ Clonidine nasal drops are erratically absorbed from the nasal mucosa and, thus, this mode of drug administration is not recommended for premedication purposes.
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Paediatric anaesthesia · Mar 2009
Randomized Controlled TrialClowns for the prevention of preoperative anxiety in children: a randomized controlled trial.
To determine if specially trained professional clowns allayed preoperative anxiety and resulted in a smooth anesthetic induction compared to the use of midazolam or no intervention. ⋯ This study found that the use of preoperative medically trained clowns for children undergoing surgery can significantly alleviate preoperative anxiety. However, clowns do not have any effect once the anesthesia mask is introduced.