Paediatric anaesthesia
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Paediatric anaesthesia · Sep 2004
Frequency of anesthesia-related complications in children with Down syndrome under general anesthesia for noncardiac procedures.
Craniofacial and cardiac anomalies of Down syndrome (DS; trisomy 21) would seem to place these patients at higher risk of anesthesia-related complications (ARCs), but to date no comprehensive large-scale study has quantified this risk. ⋯ Comprehensive reporting is needed to capture all significant adverse events. The incidences of bradycardia on induction, natural airway obstruction, and postintubation (or instrumentation) croup were significantly higher in the DS noncardiac group compared with the remaining population. Current anesthesia techniques and agents must be compared using quantitative QA data to ensure use of the safest options for each patient.
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Paediatric anaesthesia · Sep 2004
Randomized Controlled Trial Comparative Study Clinical TrialEffectiveness of morphine via thoracic epidural vs intravenous infusion on postthoracotomy pain and stress response in children.
Thoracotomy causes severe pain in the postoperative period. The aim was to evaluate effectiveness of two pain treatment methods with morphine on postthoracotomy pain and stress response. ⋯ Single dose TEP morphine offers no advantage over INF for pain treatment for thoracotomy in children and neither technique provided suppression of stress hormones in the first 24 h postoperatively.