Paediatric anaesthesia
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Paediatric anaesthesia · Oct 2004
Randomized Controlled Trial Clinical TrialRemifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery.
Remifentanil is a short acting, potent synthetic opioid that does not accumulate after infusion or repeated bolus doses. It may be rapidly titrated to the requirements of individual patients. Titrated infusion of remifentanil may be able to provide potent analgesia required for pediatric cardiac surgery and obtund the stress response in theater whilst not having the persistent respiratory depression and sedation seen with longer acting opioids. ⋯ The only significant difference was in glucose in the postbypass time periods. Although statistically significant, this difference is insufficient evidence of increased stress in the remifentanil group. The results show that in the patients studied there was no clinically important difference between the two techniques.
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Paediatric anaesthesia · Oct 2004
Comment Letter Case ReportsCardiac arrest in a patient with Larsen syndrome under sevoflurane anesthesia.
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Paediatric anaesthesia · Oct 2004
Randomized Controlled Trial Comparative Study Clinical TrialCaudal analgesia in children: S(+)-ketamine vs S(+)-ketamine plus clonidine.
The aim of this study was to evaluate postoperative analgesia provided by caudal S(+)-ketamine and S(+)-ketamine plus clonidine without local anesthetic. ⋯ Caudal S(+)-ketamine 1 mg x kg(-1) and S(+)-ketamine 0.5 mg x kg(-1) plus clonidine 1 microg x kg(-1) are safe and provide effective postoperative analgesia in children without adverse effects.
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Paediatric anaesthesia · Oct 2004
Randomized Controlled Trial Clinical TrialEffects of low dose ketamine before induction on propofol anesthesia for pediatric magnetic resonance imaging.
We aimed to investigate effects of low dose ketamine before induction on propofol anesthesia for children undergoing magnetic resonance imaging (MRI). ⋯ Intravenous administration of low dose ketamine before induction and maintenance with propofol preserves hemodynamic stability without changing the duration and the quality of recovery compared with propofol alone.
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Paediatric anaesthesia · Oct 2004
Randomized Controlled Trial Clinical TrialPostoperative behavioral changes following anesthesia with sevoflurane.
Behavioral disturbance following hospitalization is a relatively frequent event, some children still having negative behavioral changes (NBC) 1 month following their operation. Sevoflurane has a propensity to induce 'excitement' during induction of anaesthesia, and delirium in the immediate postoperative phase. The aim of this study was to evaluate whether this translates into prolonged behavioral change. ⋯ Children anesthetized with sevoflurane exhibit more immediate postoperative distress than those anesthetized with halothane. This difference is not carried over into the longer posthospital period. Negative behavioral changes occur more frequently with decreasing age.