Paediatric anaesthesia
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We describe a child who developed acidosis, hyperkalaemia and cyanosis while emerging from an otherwise uneventful anaesthetic. A diagnosis of tumour lysis syndrome was suspected and confirmed biochemically. Although this syndrome is usually associated with chemotherapy and has been described to occur spontaneously, it has not previously been reported as being associated with anaesthesia.
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Paediatric anaesthesia · Mar 2001
Randomized Controlled Trial Clinical TrialPharmacokinetics of oral diclofenac and acetaminophen in children after surgery.
Our aim was to study the pharmacokinetics and pain scores following administration of single oral doses of either diclofenac or high-dose acetaminophen (paracetamol). ⋯ The achieved concentrations of diclofenac and acetaminophen were not able to significantly reduce the children's pain score during the 5 h postingestion study period. Analgesic plasma acetaminophen concentrations may be higher than those required for antipyresis.
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Paediatric anaesthesia · Mar 2001
Aspiration and regurgitation prophylaxis in paediatric anaesthesia.
Surveys of aspiration prophylaxis in paediatric anaesthesia do not exist. ⋯ Perceived risk factors vary with "experience": hiatus hernia, difficult intubation and cerebral palsy are less important whereas previous aspiration and renal failure appear to be more important for paediatric anaesthetists with less than 10 years in paediatric anaesthetic practice.