Medicina intensiva
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Plasmapheresis is an extracorporeal technique that eliminates macromolecules involved in pathological processes from plasma. A review is made of the technical aspects, main indications in critical care and potential complications of plasmapheresis, as well as of other extracorporeal filtration techniques such as endotoxin-removal columns and other devices designed to eliminate cytokines or modulate the inflammatory immune response in critical patients.
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Multicenter Study
End-of-life practices in patients with devastating brain injury in Spain: implications for organ donation.
To describe end-of-life care practices relevant to organ donation in patients with devastating brain injury in Spain. ⋯ Although deceased donation is optimized in Spain, there are still opportunities for improvement in the identification of possible donors outside the ICU and in the consideration of donation after circulatory death in patients who die following the withdrawal of life-sustaining therapy.
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Observational Study
Estimation of potential donors after cardiocirculatory death in Elche University General Hospital (Alicante, Spain).
To evaluate the number and characteristics of potential organ donors among cardiocirculatory death cases. ⋯ Implementing a non-heart beating donation protocol in our hospital could increase the donation potential by 8-9 donors a year.
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A study is made of the influence of preemptive hemodynamic intervention restricting fluid administration upon the development of oleic acid-induced lung injury. ⋯ In this experimental model of early lung injury, lung edema progression was attenuated by preemptively restricting the administration of fluids.