Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Apr 2002
Utilization pattern of metamizole in northern Sweden and risk estimates of agranulocytosis.
This study was carried out in order to investigate the utilization pattern of metamizole to better estimate the quantitative risk of agranulocytosis since a cluster of such cases have been observed in Sweden. ⋯ This study indicates that in most inpatients the use of metamizole in northern Sweden was within the approved indications for the drug. However, a considerable number of outpatients received the drug for a longer time than recommended and this may carry an increased risk for developing agranulocytosis.