Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Sep 2003
Benzodiazepine utilization patterns in Alzheimer's disease patients.
Benzodiazepines (BZD) are commonly prescribed in the elderly. Persons with dementia may be at a greater risk of adverse reactions of BZD such as cognitive impairment. ⋯ Alzheimer's disease patients are frequently prescribed BZD. A low score of MMSE (< 24) is associated with a decreased use of BZD. These results suggest important differences in BZD use patterns among persons with Alzheimer's disease.
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Pharmacoepidemiol Drug Saf · Sep 2003
Multicenter Study Comparative StudyA case-control study of acetaminophen use in relation to the risk of first myocardial infarction in men.
Experimental evidence raises the possibility that acetaminophen use could reduce the risk of myocardial infarction (MI). We assessed the relation of acetaminophen use, and also of aspirin use, to first MI in a case-control study. ⋯ While our results raise the possibility of a protective effect of long-term regular acetaminophen use against first MI, they are compatible with no effect. The data suggest a potential protective effect of long-term regular aspirin use.