Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Sep 2008
Comparative StudyBenzodiazepine use in all alcohol consumers predicts use of opioids in patients 20 years later--a follow-up study of 13,390 men and women aged 40-42 years.
To evaluate the effect of the consumption of benzodiazepines at age 40-42 years on prescription of opioids later in life. ⋯ In this study population, a history of benzodiazepine use raised the chance of being prescribed opioids later in life among those who also used alcohol.