Pharmacoepidemiology and drug safety
-
Pharmacoepidemiol Drug Saf · May 2015
Impact of antibiotic exposure on the risk of colorectal cancer.
Gut microbiota has been postulated to serve as a significant promoter of CRC formation, and colonic dysbiosis was previously reported in CRC tissue. Our aim was to evaluate the association between the type and cumulative duration of antibiotic exposure and CRC risk. ⋯ Past exposure to multiple courses of penicillins is related to a modest elevation in CRC risk.