Pharmacoepidemiology and drug safety
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Pharmacoepidemiol Drug Saf · Apr 2020
Age and postoperative opioid prescriptions: a population-based cohort study of opioid-naïve adults.
Opioids are commonly prescribed for acute pain after surgery. However, it is unclear whether these prescriptions are usually modified to account for patient age and, in particular, opioid-related risks among older adults. We therefore sought to describe postoperative opioid prescriptions filled by opioid-naïve adults undergoing four common surgical procedures. ⋯ The proportion of opioid-naïve patients filling postoperative opioid prescriptions decreases with age. However, postoperative opioid prescription dosage is not typically different in older adults.
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Pharmacoepidemiol Drug Saf · Apr 2020
Observational StudyChronic opioid use in women following hysterectomy: Patterns and predictors.
Most women are prescribed an opioid after hysterectomy. The goal of this study was to determine the association between initial opioid prescribing characteristics and chronic opioid use after hysterectomy. ⋯ Initial opioid prescribing characteristics are associated with the risk of chronic opioid use after hysterectomy. Prescribing lower daily doses and shorter days' supply of opioids to women after hysterectomy may result in lower risk of chronic opioid use.