American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Dec 1993
Peritoneal fluid concentrations of the cytokine RANTES correlate with the severity of endometriosis.
Endometriosis is a common gynecologic disorder in which the concentration and activation of peritoneal macrophages are increased. The goal of this study was to quantify pelvic fluid concentrations of two cytokines involved in macrophage recruitment and activation. ⋯ The findings indicate that RANTES, a cytokine with potent chemotactic activity for human monocytes, may play an important role in the recruitment of peritoneal macrophages in endometriosis.