American journal of obstetrics and gynecology
-
Am. J. Obstet. Gynecol. · Aug 1997
Randomized Controlled Trial Clinical TrialRandomized trial of two doses of the prostaglandin E1 analog misoprostol for labor induction.
Our purpose was to compare the safety and effectiveness of intravaginally administered misoprostol at doses of 25 micrograms and 50 micrograms for indicated labor induction in patients with an unfavorable cervix. ⋯ Although a dose of 50 micrograms is associated with a shorter start-to-delivery interval and a higher incidence of vaginal delivery after one dose, 25 micrograms of intravaginal misoprostol is effective and associated with a lower incidence of tachysystole and cord pH values < 7.16.
-
Am. J. Obstet. Gynecol. · Aug 1997
Can flow cytometric detection of platelet activation early in pregnancy predict the occurrence of preeclampsia? A prospective study.
An increased platelet activation status is present in patients with preeclampsia. Our purpose was (1) to establish by means of flow cytometry whether platelets circulate in an activated state during the first and second trimesters of pregnancy and (2) to establish whether early platelet activation predicts the onset of preeclampsia. ⋯ Increased first-trimester CD63 expression is an independent risk factor for development of preeclampsia. CD63 expression might be useful to identify a subgroup of patients with a high risk for development of preeclampsia, especially in combination with first-trimester antenatal diastolic blood pressure. This method of patient selection may enable more efficient intervention studies in patients at risk than do the selection methods used so far.
-
Am. J. Obstet. Gynecol. · Aug 1997
Case ReportsParental rights at the birth of a near-viable infant: conflicting perspectives.
Our purpose was to clarify the roles of parents and caregivers in making decisions for resuscitation of near-viable infants. ⋯ Effective communication is essential to prevent misunderstanding and conflicts. In most instances parents are the best decision makers for a near-viable infant. Parental rights are limited by best interests of the infant.