American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Sep 2001
Randomized Controlled Trial Comparative Study Clinical TrialA randomized trial that compared oral cefixime and intramuscular ceftriaxone for the treatment of gonorrhea in pregnancy.
The purpose of this study was to evaluate prospectively the Centers for Disease Control recommendations for the treatment of gonococcal infection in pregnancy. ⋯ Both intramuscular ceftriaxone 125 mg and oral cefixime 400 mg appear to be effective for the treatment of gonococcal infection in pregnancy.
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Am. J. Obstet. Gynecol. · Sep 2001
The Preterm Prediction Study: toward a multiple-marker test for spontaneous preterm birth.
The Preterm Prediction Study evaluated 28 potential biologic markers for spontaneous preterm birth in asymptomatic women at 23 to 24 weeks gestational age. This analysis compares those markers individually and in combination for an association with spontaneous preterm birth at <32 and <35 weeks gestational age. ⋯ Overlap among the strongest biologic markers for spontaneous preterm birth is small. This suggests that the use of tests such as maternal serum alpha-fetoprotein, alkaline phosphatase, and granulocyte colony-stimulating factor as a group or adding their results to fetal fibronectin test and cervical length test results may enhance our ability to predict spontaneous preterm birth and that the development of a multiple-marker test for spontaneous preterm birth is feasible.
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Destructive procedures to permit vaginal delivery of the fetus with hydrocephalus are rarely performed. ⋯ A reappraisal of the proper role of cephalocentesis in modern obstetrics is offered.