American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Oct 2004
Randomized Controlled Trial Comparative Study Clinical TrialA clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy.
The purpose of this study was to compare the analgesic activity of 2 doses of parecoxib sodium, ketorolac, and morphine with placebo after gynecologic surgery that requires laparotomy. ⋯ Parecoxib sodium is an effective analgesic in the management of acute postoperative pain after laparotomy surgery.
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Am. J. Obstet. Gynecol. · Oct 2004
Randomized Controlled Trial Clinical TrialMeperidine for dystocia during the first stage of labor: A randomized controlled trial.
This study was undertaken to evaluate whether the administration of meperidine decreases the length of labor in patients with a diagnosis of dystocia during the first stage of labor. ⋯ Because of the absence of any benefits in patients with dystocia in labor and the presence of harmful effects on neonatal outcomes, meperidine should not be used during labor for this specific indication.
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Am. J. Obstet. Gynecol. · Oct 2004
Perinatal intervention and neonatal outcomes near the limit of viability.
The purpose of this study was to evaluate trends in the level of obstetric and neonatal intervention near the limit of viability and perinatal morbidity and mortality rates over time. ⋯ Obstetric intervention and aggressive neonatal resuscitation have increased for pregnancies delivered between 23 and 26 weeks of gestation over the past decade. Although survival has increased over time and with advancing gestational age at delivery, short-term morbidity in survivors is similar, regardless of gestational age in this cohort. A brief delay in delivery of those pregnancies who are at risk for delivery between 23 and 26 weeks of gestation may improve survival, although short-term morbidity in survivors will not be affected substantially.