American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Jul 2008
Historical ArticleMaternal death in the 21st century: causes, prevention, and relationship to cesarean delivery.
We sought to examine etiology and preventability of maternal death and the causal relationship of cesarean delivery to maternal death in a series of approximately 1.5 million deliveries between 2000 and 2006. ⋯ Most maternal deaths are not preventable. Preventable deaths are equally likely to result from actions by nonmedical persons as from provider error. Given the diversity of causes of maternal death, no systematic reduction in maternal death rate in the United States can be expected unless all women undergoing cesarean delivery receive thromboembolism prophylaxis. Such a policy would be expected to eliminate any statistical difference in death rates caused by cesarean and vaginal delivery.
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Am. J. Obstet. Gynecol. · Jul 2008
Incidence and risk factors of amniotic fluid embolisms: a population-based study on 3 million births in the United States.
Amniotic fluid embolism (AFE) is a condition occurring during delivery that can lead to severe maternal morbidity and mortality. Given the rarity of its occurrence, current estimates and predictors of the incidence and outcomes are often difficult to obtain. ⋯ AFE is a rare but serious condition that is associated with advanced maternal age, placental pathologies, and cesarean deliveries. Further research on the treatment of this condition is necessary.
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Am. J. Obstet. Gynecol. · Jul 2008
Postovariectomy weight gain in female rats is reversed by estrogen receptor alpha agonist, propylpyrazoletriol.
The objective of this study was to distinguish the role of specific estrogen receptors (ERs), ERalpha and ERbeta, on body weight regulation using a rat model of weight gain subsequent to menopause. ⋯ These results suggest that the activation of ERalpha is important in regulating body weight.