American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Jan 2016
Randomized Controlled Trial Multicenter StudyCervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial.
Preterm birth is the leading cause of neonatal death and handicap in survivors. Although twins are found in 1.5% of pregnancies they account for about 25% of preterm births. Randomized controlled trials in singleton pregnancies reported that the prophylactic use of progestogens, cervical cerclage and cervical pessary reduce significantly the rate of early preterm birth. In twin pregnancies, progestogens and cervical cerclage have been shown to be ineffective in reducing preterm birth. ⋯ In women with twin pregnancy, routine treatment with cervical pessary does not reduce the rate of spontaneous early preterm birth.