American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Aug 2009
Randomized Controlled Trial Comparative StudyComparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial.
The purpose of this study was to compare the effectiveness of topically applied lidocaine-prilocaine (EMLA) cream with local anesthetic infiltration in the reduction of pain during perineal suturing after childbirth. ⋯ EMLA cream appears to be an effective and satisfactory alternative to local anesthetic infiltration for the relief of pain during perineal repair.
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Am. J. Obstet. Gynecol. · Jul 2009
Von Willebrand disease and other bleeding disorders in women: consensus on diagnosis and management from an international expert panel.
Reproductive tract bleeding in women is a naturally occurring event during menstruation and childbirth. In women with menorrhagia, however, congenital bleeding disorders historically have been underdiagnosed. This consensus is intended to allow physicians to better recognize bleeding disorders as a cause of menorrhagia and consequently offer effective disease-specific therapies.
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Am. J. Obstet. Gynecol. · Jun 2009
Review Meta AnalysisAntenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks' gestation: a systematic review and metaanalysis.
We conducted a systematic review and metaanalysis of randomized controlled trials to determine whether magnesium sulfate administered to women at risk of preterm delivery before 34 weeks of gestation may reduce the risk of cerebral palsy in their children. Six trials involving 4796 women and 5357 infants were included. ⋯ Minor side effects were more frequent among women receiving magnesium sulfate. In conclusion, magnesium sulfate administered to women at risk of delivery before 34 weeks of gestation reduces the risk of cerebral palsy.
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Am. J. Obstet. Gynecol. · Jun 2009
Meta AnalysisExtraabdominal vs intraabdominal uterine repair at cesarean delivery: a metaanalysis.
Cesarean section delivery is a commonly performed surgical procedure, and rates of cesarean delivery are increasing. Previous randomized trials that compared extraabdominal and intraabdominal uterine repair at cesarean section delivery have yielded conflicting results. ⋯ No differences in complication rates were found between extraabdominal and intraabdominal repair at cesarean section delivery; both techniques are valid surgical options.
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Three large, randomized placebo-controlled trials of antenatal magnesium sulfate (MgSO(4)) for fetal neuroprotection have recently been conducted and reported. The results of these trials provide strong support for the utilization of MgSO(4) to lower the risk of cerebral palsy among the survivors of early preterm birth. In the United States, the use of MgSO(4) for fetal neuroprotection has the potential to prevent 1000 cases of handicapping cerebral palsy annually.