American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Jun 2009
Review Meta AnalysisAntenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks' gestation: a systematic review and metaanalysis.
We conducted a systematic review and metaanalysis of randomized controlled trials to determine whether magnesium sulfate administered to women at risk of preterm delivery before 34 weeks of gestation may reduce the risk of cerebral palsy in their children. Six trials involving 4796 women and 5357 infants were included. ⋯ Minor side effects were more frequent among women receiving magnesium sulfate. In conclusion, magnesium sulfate administered to women at risk of delivery before 34 weeks of gestation reduces the risk of cerebral palsy.
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Am. J. Obstet. Gynecol. · Jun 2009
Meta AnalysisExtraabdominal vs intraabdominal uterine repair at cesarean delivery: a metaanalysis.
Cesarean section delivery is a commonly performed surgical procedure, and rates of cesarean delivery are increasing. Previous randomized trials that compared extraabdominal and intraabdominal uterine repair at cesarean section delivery have yielded conflicting results. ⋯ No differences in complication rates were found between extraabdominal and intraabdominal repair at cesarean section delivery; both techniques are valid surgical options.
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Three large, randomized placebo-controlled trials of antenatal magnesium sulfate (MgSO(4)) for fetal neuroprotection have recently been conducted and reported. The results of these trials provide strong support for the utilization of MgSO(4) to lower the risk of cerebral palsy among the survivors of early preterm birth. In the United States, the use of MgSO(4) for fetal neuroprotection has the potential to prevent 1000 cases of handicapping cerebral palsy annually.
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Am. J. Obstet. Gynecol. · Jun 2009
Global measures of quality- and patient safety-related childbirth outcomes: should we monitor adverse or ideal rates?
The objective of the study was to propose a new measure of ideal childbirth outcome, based on the proportion of women delivering without maternal or newborn childbirth morbidity. ⋯ The ID rate is a simple hospital-level measure of childbirth outcome that is easy to calculate and interpret.