American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Feb 2002
Pulmonary embolism and stroke in relation to pregnancy: how can high-risk women be identified?
Risks of circulatory diseases are increased substantially during late pregnancy and around the time of delivery. This study was undertaken to determine whether preeclampsia, multiple pregnancy, or cesarean delivery account for the majority of pregnancy-related risks of pulmonary embolism and stroke (caused by hemorrhage, infarction, and intracranial venous thrombosis). ⋯ Preeclampsia, multiple birth, and cesarean delivery are important risk factors for pulmonary embolism and stroke, but they do not account for the majority of the excess risks associated with pregnancy.
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Am. J. Obstet. Gynecol. · Jan 2002
Resistance artery smooth muscle function in pregnancy and preeclampsia.
The purpose of this study was to investigate whether the altered vascular resistance in pregnancy and preeclampsia results from alterations in intrinsic vascular smooth muscle properties or from external influences on vascular smooth muscle function. ⋯ Vascular smooth muscle calcium sensitivity is increased in preeclampsia.
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Am. J. Obstet. Gynecol. · Jan 2002
Randomized Controlled Trial Multicenter Study Clinical TrialAdverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia.
The current literature emphasizes increased risk of adverse outcomes in the presence of proteinuria and hypertension. The objective of this study was to compare the frequency of adverse fetal outcomes in women who developed hypertensive disorders with or without proteinuria. ⋯ In women who have gestational hypertension or preeclampsia, increased rates of preterm delivery and delivery of small-for-gestational-age infants are present only in those with severe hypertension. In these women, the presence of proteinuria does not influence perinatal outcome.
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Am. J. Obstet. Gynecol. · Dec 2001
Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders.
To evaluate the psychometric properties of the Pelvic Floor Distress Inventory (PFDI) and the Pelvic Floor Impact Questionnaire (PFIQ). ⋯ The PFDI and the PFIQ are reliable, valid, condition-specific quality of life instruments for women with pelvic floor disorders.
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Am. J. Obstet. Gynecol. · Nov 2001
Does the combined antenatal use of corticosteroids and antibiotics increase late-onset neonatal sepsis in the very low birth weight infant?
The purpose of this study was to determine whether the combined use of maternal antenatal corticosteroids and antibiotic therapy is associated with an increased risk of late-onset neonatal sepsis among very low birth weight infants. ⋯ The combined use of maternal corticosteroids and antibiotic therapy is not associated with an increased risk for late-onset neonatal sepsis.