American journal of obstetrics and gynecology
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Am. J. Obstet. Gynecol. · Sep 1993
Stimulation and inhibition of N-methyl-D-aspartate receptors in rats: developing a seizure model.
The objective of this study was to develop an experimental rat hippocampal seizure model based on the stimulatory effects of N-methyl-D-aspartate and to determine the inhibitory effects of MK-801 on N-methyl-D-aspartate-induced seizures. ⋯ Intracranial injection of 20 micrograms of N-methyl-D-aspartate produced reliable hippocampal seizure activity without mortality. MK-801 at a dose of 1 mg/kg injected intraperitoneally had significant inhibitory effects on this seizure model.
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A historic survey of the literature and nine recent examples of uterine packing for control of postpartum hemorrhage are presented. Once a frequently practiced art, intracavitary packing for the control of uterine postpartum bleeding became a lost skill to most physicians after the 1950s. Objections to the practice are presented through a review of the literature. ⋯ Whether used early or late in patient management, uterine packing for the control of postpartum hemorrhage is a safe, quick, and effective procedure.
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Am. J. Obstet. Gynecol. · Aug 1993
A twenty-year retrospective analysis of the efficacy of epidural analgesia-anesthesia when administered and/or managed by obstetricians.
The purpose of this study was to retrospectively determine the safety and efficacy of epidural anesthesia when administered by obstetricians in a community hospital. ⋯ Over a 20-year period epidural analgesia or anesthesia has been an effective and safe procedure when performed and supervised by obstetricians-gynecologists in a community hospital.
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Am. J. Obstet. Gynecol. · Jul 1993
First-trimester transabdominal multifetal pregnancy reduction: a report of two hundred completed cases.
Multifetal pregnancy reduction has been proposed as a way to reduce the risk of preterm delivery in women who conceive three or more fetuses. This communication presents the outcome of 200 consecutive multifetal pregnancies in which reduction to a smaller number of fetuses was accomplished. ⋯ The incidence of intrauterine growth retardation was not increased over that anticipated in a population of twins.