American journal of ophthalmology
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Case Reports
Repair of cicatricial ectropion in an infant with harlequin ichthyosis using engineered human skin.
To report the use of an Apligraf (Organogenesis, Inc., Canton, Massachusetts, USA) human skin equivalent for repair of cicatricial ectropion in a patient with harlequin ichthyosis. ⋯ Apligraf human skin equivalent facilitated the repair of cicatricial ectropion in a child with harlequin ichthyosis.
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To determine the value of aqueous humor analysis for confirming the diagnosis of ocular toxoplasmosis in patients who present with atypical clinical features and to relate the results of local antibody production and polymerase chain reaction (PCR) with the extent of active retinitis and the immune status of the patient. ⋯ Although in the present study, the sensitivity and specificity of the aqueous humor PCR and Goldman-Witmer coefficient could not be ascertained in the laboratory diagnosis of toxoplasmic retinochoroiditis, the PCR method appears to confirm the diagnosis in immunocompromised individuals with large atypical foci of retinitis. Conversely, determination of local antibody production may be appropriate for proper diagnosis in immunocompetent individuals presenting with small foci of retinitis.
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To describe a simple technique that detects a subtle relative afferent pupillary defect. ⋯ Using slit-lamp magnification, the examiner may observe small amplitudes of pupillary movement in the evaluation of a relative afferent pupillary defect.
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Randomized Controlled Trial Comparative Study Clinical Trial
Effect of sildenafil citrate (Viagra) on retinal blood vessel diameter.
The present investigation was conducted to evaluate the effect of sildenafil citrate (Viagra, Pfizer Inc., New York, NY) on retinal blood vessel diameter. ⋯ These data suggest that at the maximum therapeutic dose used clinically (100 mg), sildenafil does not have a significant effect on retinal vascular caliber.
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Case Reports
Osseous choristoma of the conjunctiva simulating extraocular extension of retinoblastoma.
To report the clinicopathologic features of an epibulbar osseous choristoma simulating extraocular extension of retinoblastoma. ⋯ An epibulbar osseous choristoma can simulate extraocular extension of retinoblastoma in an eye harboring the intraocular malignancy.