Neuroimaging clinics of North America
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Neuroimaging Clin. N. Am. · Nov 1998
ReviewProton MR spectroscopy in inflammatory and infectious brain disorders.
This article reviews the proton MR spectroscopy literature regarding brain infarction and inflammatory diseases. We examine the salient findings reported for bacterial abscesses, intracranial tuberculomas, Creutzfeldt-Jakob disease, herpes simplex encephalitis and HIV. These processes demonstrate specific metabolic profiles which may be useful in differential diagnosis. The results reported in the literature support the view that MR spectroscopy can be employed in longitudinal studies to monitor the response to therapy and therefore may lead to individual optimized treatment effectiveness.
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Primary central nervous system tumors are the most common solid tumors in children. Their overall frequency is second only to that of leukemia. Many brain tumors in children are relatively benign and can be successfully treated with surgery or radiation therapy, but progress in treating the malignant forms of these neoplasms lags behind that for leukemias and other solid tumors. This article discusses how MR spectroscopy is used to manage the individualized treatment of children with brain tumors.