Neuroimaging clinics of North America
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The field of statistics makes valuable contributions to functional neuroimaging research by establishing procedures for the design and conduct of neuroimaging experiments and providing tools for objectively quantifying and measuring the strength of scientific evidence provided by the data. Two common functional neuroimaging research objectives include detecting brain regions that reveal task-related alterations in measured brain activity (activations) and identifying highly correlated brain regions that exhibit similar patterns of activity over time (functional connectivity). This article highlights various statistical procedures for analyzing data from activation studies and functional connectivity studies, focusing on functional magnetic resonance imaging (fMRI) and positron emission tomography (PET) data. Also discussed are emerging statistical methods for prediction using fMRI and PET data, which stand to increase the translational significance of functional neuroimaging data to clinical practice.
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Neuroimaging Clin. N. Am. · Nov 2007
ReviewImaging of the mind: yesterday's triumphs and tomorrow's challenges.
Imaging of the mind involves an understanding of the brain and imaging technology. Much progress has been made over the past 400 years in defining the mind and developing tools for its investigation. ⋯ Scientific imaging has dramatically increased in power over the past 2 decades and is now a critical tool for studying the brain, the physical seat of the mind. Whether the mind can be imaged remains to be seen.