International archives of allergy and immunology
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Int. Arch. Allergy Immunol. · May 1998
Case Reports Comparative StudyPredominant implication of IL-5 in acute eosinophilic pneumonia: comparison with chronic eosinophilic pneumonia.
Acute eosinophilic pneumonia (AEP) is a rare disease with unknown etiology. To examine pathophysiology of AEP we measured the cell number of eosinophils and eosinophil active cytokines in the peripheral blood and bronchoalveolar lavage fluid (BALF) of AEP patients and compared the levels with those measured in chronic eosinophilic pneumonia (CEP) patients. ⋯ AEP is a disease in which eosinophil active cytokine IL-5 is predominantly involved; CEP is not. The factors involving eosinophil infiltration to inflammatory loci differ between AEP and CEP.