International archives of allergy and immunology
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Int. Arch. Allergy Immunol. · Jun 2000
Comparative Study Clinical TrialEffects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism.
Dietary sources of alpha-linolenic acid, such as perilla seed oil, may have the capacity to inhibit the generation of leukotrienes (LTs) by leucocytes in patients with asthma, as has been reported with the consumption of other long-chain n-3 fatty acids. ⋯ Dietary supplementation with perilla seed oil in selected patients with asthma suppresses the generation of LTC4 and is associated with clinical features such as respiratory function and lipometabolism.