International archives of allergy and immunology
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Int. Arch. Allergy Immunol. · Sep 2003
Ana o 2, a major cashew (Anacardium occidentale L.) nut allergen of the legumin family.
We recently cloned and described a vicilin and showed it to be a major cashew allergen. Additional IgE-reactive cashew peptides of the legumin group and 2S albumin families have also been reported. Here, we attempt to clone, express and characterize a second major cashew allergen. ⋯ We conclude that this legumin-like protein is a major allergen in cashew nut.