The American journal of the medical sciences
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Women with acute myocardial infarction (AMI) have poorer clinical outcomes than men. Elderly women present high risk of developing frailty and frail women with AMI have a higher prevalence of functional impairments than men on presentation, including physical and cognitive impairment. ⋯ Cognitive and physical decline are very common in frail women, and their prevalence increases with age. On the basis of existing literature, we may speculate that frail women with AMI should be studied with 5-m gait speed test and Mini-Mental State Examination before hospital discharge, for a better evaluation of physical status and global cognitive function.
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Comparative Study
Lower Post Myocardial Infarction Mortality Among Women Treated at Veterans Affairs Hospitals Compared to Men.
There is conflicting evidence about whether mortality after myocardial infarction is higher among women than among men. This study aimed to compare sex differences in post myocardial infarction mortality in the Veterans Affairs system, a setting where the predominant subjects are men. ⋯ In a health care system where the predominant subjects are men, women had better short- and long-term survival than men after an acute myocardial infarction. Further investigation is warranted to determine the reasons behind the improved outcomes in women post myocardial infarction in the veteran population.
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Physical activity plays an important role in the prevention of cardio-metabolic diseases. The present study evaluated the effect of habitual physical activity on body composition, peak oxygen consumption, cardiac and metabolic function. ⋯ Increased levels of habitual physical activity improve body composition and peak oxygen consumption but appears to have limited effect cardio-metabolic function in middle-aged women.
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Familial dysalbuminemic hyperthyroxinemia (FDH) is a rare autosomal dominant disorder whose clinical characteristics remain incompletely understood, we investigated the role of albumin gene mutation in relation to miscarriage rate in a large pedigree of FDH followed up for 4 years. ⋯ Albumin gene variant (R218S) not only causes FDH but also may be associated with a higher risk of miscarriages, although the growth of their children appears not to be affected by the age of 2 years.