Journal of the European Academy of Dermatology and Venereology : JEADV
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J Eur Acad Dermatol Venereol · Jan 2007
Vascular adhesion protein-1 (VAP-1) is overexpressed in psoriatic patients.
Vascular adhesion protein (VAP)-1 is an adhesion molecule with an enzymatic activity that partakes in the migration process of lymphocytes. ⋯ Significant overexpression of VAP-1 in both lesional and non-lesional psoriatic skin and higher serum level of soluble VAP-1 in psoriatic patients may indicate the role of VAP-1 in chronic inflammation occurring in psoriasis. However, because of lack of correlation between soluble VAP-1 serum levels and psoriasis severity this hypothesis needs further investigation.