Journal of the European Academy of Dermatology and Venereology : JEADV
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J Eur Acad Dermatol Venereol · Jan 2007
Vascular adhesion protein-1 (VAP-1) is overexpressed in psoriatic patients.
Vascular adhesion protein (VAP)-1 is an adhesion molecule with an enzymatic activity that partakes in the migration process of lymphocytes. ⋯ Significant overexpression of VAP-1 in both lesional and non-lesional psoriatic skin and higher serum level of soluble VAP-1 in psoriatic patients may indicate the role of VAP-1 in chronic inflammation occurring in psoriasis. However, because of lack of correlation between soluble VAP-1 serum levels and psoriasis severity this hypothesis needs further investigation.
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J Eur Acad Dermatol Venereol · Nov 2006
Clinical TrialThe effectiveness of intermittent isotretinoin treatment in mild or moderate acne.
Isotretinoin is the only drug that affects almost all factors in acne pathogenesis. Recently, its use for the treatment of chronic mild or moderate acne unresponsive to long-term antibiotic therapy, and with a tendency to cause scarring and leading to negative psychological effects, has became popular. The aim of the study was to investigate the effectiveness of intermittent isotretinoin treatment in mild or moderate acne. ⋯ Intermittent isotretinoin treatment was found to be a safe and effective choice for patients with mild or moderate acne.
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J Eur Acad Dermatol Venereol · Aug 2006
Clinical TrialCryotherapy in the treatment of pyogenic granuloma.
Pyogenic granuloma is a benign, acquired, proliferative vascular lesion of the skin and mucous membranes. Many different treatments have been used for pyogenic granuloma with variable success rates. ⋯ We believe that pyogenic granuloma can be treated simply and effectively with cryotherapy.