The American journal of psychiatry
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Randomized Controlled Trial Clinical Trial
Double-blind, fixed-dose, placebo-controlled study of paroxetine in the treatment of panic disorder.
This study was designed to determine the minimum paroxetine dose effective for treating panic disorder. ⋯ Paroxetine is an effective and well-tolerated short-term treatment of panic disorder. The minimum dose demonstrated to be significantly superior to placebo was 40 mg/day, although some patients did respond at lower doses.