Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
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Support Care Cancer · Jun 2004
ReviewSystematic review of the efficacy of antiemetics in the treatment of nausea in patients with far-advanced cancer.
To systematically review studies of antiemetics used in the treatment of nausea in patients with far-advanced cancer. ⋯ Evidence supporting the existing consensus-based guidelines for management of nausea and vomiting in advanced cancer is sparse. Current approaches to treatment based on the neuropharmacology of the emetic pathway may be inappropriate in this setting. Well-designed studies of the impact of "standard" management and novel agents on nausea and vomiting in palliative populations are needed.