Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Jul 2005
Randomized Controlled Trial Clinical TrialTreatment of knee osteoarthritis with pulsed electromagnetic fields: a randomized, double-blind, placebo-controlled study.
The investigation aimed at determining the effectiveness of pulsed electromagnetic fields (PEMF) in the treatment of osteoarthritis (OA) of the knee by conducting a randomized, double-blind, placebo-controlled clinical trial. ⋯ Applying between group analysis we were unable to demonstrate a beneficial symptomatic effect of PEMF in the treatment of knee OA in all patients. However, in patients <65 years of age there is significant and beneficial effect of treatment related to stiffness.
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Osteoarthr. Cartil. · Jul 2005
Comparative StudyUltrasonographic findings in knee osteoarthritis: a comparative study with clinical and radiographic assessment.
To compare ultrasonographic (US) findings with clinical and radiographic assessment in knee osteoarthritis (OA). ⋯ Knee effusion and MMP with MCLD are associated with pain in knee OA. In addition, MMP may contribute to the radiographic medial FT space narrowing. We propose US for assessing periarticular and intraarticular abnormalities involved in the pathophysiology of knee OA.
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Osteoarthr. Cartil. · Jul 2005
The detached osteochondral fragment as a source of cells for autologous chondrocyte implantation (ACI) in the ankle joint.
Autologous chondrocyte implantation (ACI) has been successfully used for the treatment of osteochondral lesions of the talus. One of the main problems of this surgical strategy is related to the harvesting of the cartilage slice from a healthy knee. The aim of this study was to examine the capacity of chondrocytes harvested from a detached osteochondral fragment to proliferate and to serve as a source of viable cells for ACI in the repair of ankle cartilage defects. ⋯ The good results achieved with this strategy indicate that cells derived from the lesioned area may be useful in the treatment of osteochondral defects of the talus.