Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Aug 2006
Comparative StudyA quantitative approach to measure joint pain in experimental osteoarthritis--evidence of a role for nitric oxide.
To describe a method to study joint pain in experimental osteoarthritis (OA) and to study nitric oxide (NO) participation in experimental OA. ⋯ We describe a method to quantitate joint pain associated to weight bearing in the ACLT model. The joint pain is sensitive to classical antinociceptive compounds. NO release is associated to joint pain though NOS inhibition does not inhibit ongoing pain.