Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Sep 2011
Multicenter StudyPsychological health impact on 2-year changes in pain and function in persons with knee pain: data from the Osteoarthritis Initiative.
We determined whether baseline depressive symptoms, knee-related confidence and general psychological distress influenced changes in pain and function during 2 years of follow-up. ⋯ The most consistent psychological predictor of yearly worsening was baseline depressive symptoms. Although a statistically robust predictor of outcome, given that change was very small and highly dependent on baseline status, our results indicate that a considerable degree of persistent depressive symptoms would be required to have a meaningful effect on future self-reported outcome.