Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Oct 2012
Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis.
To assess the influence of pre-operative X-ray changes on the response to total knee joint replacement (TKR). ⋯ Patients with more severe radiographic knee damage at the time of surgery are most likely to have substantial gains in terms of both pain relief and improved function as a result of a TKR.
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Osteoarthr. Cartil. · Oct 2012
Review Meta AnalysisQuantitative sensory testing in painful osteoarthritis: a systematic review and meta-analysis.
To systematically review the use of quantitative sensory testing (QST) in pain characterisation (phenotyping) in osteoarthritis (OA). ⋯ QST of PPTs demonstrated good ability to differentiate between people with OA and healthy controls. Lower PPTs in people with OA in affected sites may suggest peripheral, and in remote sites central, sensitisation. PPT measurement merits further evaluation as a tool for phenotyping OA pain.
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Osteoarthr. Cartil. · Oct 2012
Rasch analysis of the intermittent and constant osteoarthritis pain (ICOAP) scale.
The intermittent and constant osteoarthritis pain (ICOAP) questionnaire was developed to assess two forms of pain reported by people with osteoarthritis: intermittent and constant pain. Studies examining its measurement qualities have provided some support for its use as separate and total scales. However, it has not been previously evaluated using Rasch analysis. The current study examined the fit between data obtained from the ICOAP questionnaire and the Rasch model to determine whether it meets the requirements of interval-level measurement. ⋯ The results support the use of Constant and Intermittent subscales as unidimensional measures of pain. The Total scale can be adapted to improve fit to the Rasch model, but there are concerns over participant misfit.
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Osteoarthr. Cartil. · Oct 2012
Randomized Controlled Trial Comparative StudyComparative effectiveness of alternative clinical pathways for primary hip and knee joint replacement patients: a pragmatic randomized, controlled trial.
Total hip replacement (THR) and total knee replacement (TKR) (arthroplasty) surgery for end-stage osteoarthritis (OA) are ideal candidates for optimization through an algorithmic care pathway. Using a comparative effectiveness study design, we compared the effectiveness of a new clinical pathway (NCP) featuring central intake clinics, dedicated inpatient resources, care guidelines and efficiency benchmarks vs. the standard of care (SOC) for THR or TKR. ⋯ While effect sizes were small compared with major effects of the surgery itself, an evidence-informed clinical pathway can improve health related quality of life (HRQoL) of hip and knee arthroplasty patients with degenerative joint disorder in routine clinical practice for up to 12 months post-operatively. CLINICALTRIALS.GOV IDENTIFIER: NCT00277186.