Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Mar 2014
Sensitivity and associations with pain and body weight of an MRI definition of knee osteoarthritis compared with radiographic Kellgren and Lawrence criteria: a population-based study in middle-aged females.
Is a magnetic resonance imaging (MRI) definition for tibiofemoral osteoarthritis [(TFOAMRI) (definite osteophyte and full-thickness cartilage loss (or a combination of these factors with other MRI osteoarthritis (OA) features)] more sensitive to detect structural OA compared with the Kellgren & Lawrence (K&L) grading? And which definition shows the strongest association with (1) knee pain at baseline, (2) persistent knee pain during 2-year follow-up, (3) new onset of knee pain ±2 years later, and (4) body mass index (BMI). ⋯ TFOAMRI detects more cases of knee OA than K&L ≥ 2. Together with a better content validity and at least equal construct validity, we conclude that the TFOAMRI definition for knee OA is more sensitive in detecting structural knee OA.
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Osteoarthr. Cartil. · Mar 2014
Practice GuidelineOARSI guidelines for the non-surgical management of knee osteoarthritis.
To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis (OA), intended to inform patients, physicians, and allied healthcare professionals worldwide. ⋯ These evidence-based consensus recommendations provide guidance to patients and practitioners on treatments applicable to all individuals with knee OA, as well as therapies that can be considered according to individualized patient needs and preferences.
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Osteoarthr. Cartil. · Mar 2014
Detection of cartilage damage in femoroacetabular impingement with standardized dGEMRIC at 3 T.
This study aimed at identifying the optimal threshold value to detect cartilage lesions with Standardized delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC) at 3 T and evaluate intra- and inter-observer repeatability. ⋯ Standardized dGEMRIC at 3 T is accurate in detecting cartilage damage and could improve preoperative assessment in femoroacetabular impingement (FAI). As cartilage lesions in FAI are localized, visual inspection of the Standardized dGEMRIC maps is more accurate than an average z for the acetabular cartilage.