Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Dec 2017
Magic angle effect plays a major role in both T1rho and T2 relaxation in articular cartilage.
To investigate the effect of sample orientation on T1rho and T2 values of articular cartilage in histologically confirmed normal and abnormal regions using a whole-body 3T scanner. ⋯ Changes in T1rho and T2 values due to the magic angle effect can be several times more than that caused by degeneration, and this may significantly complicate the clinical application of T1rho and T2 as an early surrogate marker for degeneration.