Osteoarthritis and cartilage
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Osteoarthr. Cartil. · Jun 2020
Review Meta AnalysisEfficacy and safety of duloxetine in osteoarthritis or chronic low back pain: a Systematic review and meta-analysis.
To evaluate the efficacy and safety of duloxetine in the treatment of patients with osteoarthritis (OA) or chronic low back pain (CLBP). ⋯ Duloxetine had modest to moderate effects on pain relief, function improvement, mood regulation and improvement in quality of life with mild AEs in the treatment of OA or CLBP. Future RCTs should focus on comparing duloxetine with other oral drugs and assessing the long-term safety of duloxetine.