Seizure : the journal of the British Epilepsy Association
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Multicenter Study Comparative Study Clinical Trial
An open-label, add-on study of pregabalin in patients with partial seizures: a multicenter trial in Greece.
Pregabalin efficacy and safety as an adjunctive treatment for partial seizures was evaluated using an open-label, flexible-dose. ⋯ The efficacy and side-effect profile of pregabalin were similar to previous pregabalin double-blind, controlled studies. Additionally, pregabalin, as an add-on treatment for partial epilepsy, exhibits significant anti-anxiety properties.
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Comparative Study
A comparative study of health related quality of life, psychological well-being, impact of illness and stigma in epilepsy and migraine.
This study aimed to show the difference of epilepsy from another chronic neurological disorder with episodic manifestations (CDEM): migraine. Seventy persons with epilepsy (PWE), 56 persons with migraine (PWM) and 45 healthy control participants (HCs) were included. The groups were compared in terms of demographics, quality of life, depression and self-esteem. ⋯ Also, the PWM emphasized the importance of being "able to fulfil daily living, social and work activities", while the PWE emphasized the need for "independence" constantly. These results indicate that, although both migraine and epilepsy are CDEMs, they have different levels of impact on patients' lives. The impacts are socially greater in epilepsy and extend beyond the neurological condition itself.